Which CMYK profile should I select? Rich February 08, 2018 12:15 Follow The best option to select in Photoshop is U.S. Web Coated (SWOP) v2. Within Photoshop, go to Edit -> Colour settings -> Settings -> North America General Purpose 2 Within Colour settings > Working Spaces > CMYK > U.S. Web Coated (SWOP) v2 Have more questions? Submit a request 0 Comments Please sign in to leave a comment.